Best Diet Pill

Which are the Diet Pills that Meet our Safety and Effectiveness Criteria? [Top]

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Alli and Proactol diet pills are two of the safest and effective pills for weight loss. They are the safer diet pills because they belong to a class of diet pills call fat binders/blockers. Fat binders/blockers are not absorbed into the body blood system and are removed straight through the body's digestive system. This will minimised the chance of the diet pill causing any harmful reaction in the body. They are the more effective diet pills because they are backed by numerous published clinical trials and studies.

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Different Classes of Diet Pills

Diet pills can be categorised into several different classes. Common classes of weight loss pills are Fat Burners, Fat Blockers/Binders and Appetite Suppressants. Among these three common classes, diet pills belonging to the class Fat Blockers/Binders are considered safest in our opinion. Fat Blockers/Binders are "non-invasive" as they operate in your digestive tracts and are not being absorbed into the body. On the other hand, Fat Burners and Appetite Suppressants need to be absorbed into your blood stream and thus affect your body system in order to achieve weight loss effects.

Short-Listing for the Best Fat Blockers/Binders

Since we have decided on Fat Blockers/Binders, we will be focusing on selecting the best diet pills in this class. Our strictest selection criteria are whether the safety and effectiveness of the diet pill has been proven from published clinical trials/studies and whether the diet pill has a long and good track record. We have identified two diet pills that met our stringent selection criteria: Alli diet pill and Proactol diet pill. 

Alli Diet Pill

Alli is the first and only FDA approved Over-the-Counter weight loss drug see glossary. (This is different from FDA approved dietary supplement for weight loss see glossary).

Alli has been in the market for close to 10 years. (Although Alli was approved only in February 7, 2007, its active ingredient Orlistat see glossary has been used since April 23, 1999 under another brand name Xenical).

Many clinical studies and trials had since been conducted to demonstrate the safety and effectiveness of using Alli (Orlistat) . FDA was convinced that these clinical data and result were reliable and approved its use as a prescription-only weight loss drug in 1999 and over-the-counter in 2007.

Here is a small list of significant clinical studies and trials completed on Alli (Orlistat).

• XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Published in journal Diabetes Care. 2004 Jan, Volume 27, Pages 155-161.
• A 4-year clinical trial involving 3305 patients. Compared with lifestyle changes alone, orlistat plus lifestyle changes resulted in a greater reduction in the incidence of type 2 diabetes over 4 years and produced greater weight loss in a clinically representative obese population. Difference in diabetes incidence was detectable only in the IGT subgroup; weight loss was similar in subjects with IGT or NGT [correction].
• Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group. Published in medical journal The Lancet. 1998 Jul 18, Volume 352, Issue 9123, Pages 167-172.
• A 2-year clinical trial conducted at 15 European centres involving 743 patients. Orlistat taken with an appropriate diet promotes clinically significant weight loss and reduces weight regain in obese patients over a 2-year period. The use of orlistat beyond 2 years needs careful monitoring with respect to efficacy and adverse events.

Proactol Diet Pill

Proactol has received the CE mark (as a medical device under The Medical Devices Directive MDD 93/42/EEC) to allow for sale in the European Economic Area and FDA approval to allow for sale in U.S. as a dietary supplement for weight loss see glossary.

Proactol has been in the market for close to 10 years. (Although Proactol was officially launched in the market from March 28, 2007, its active ingredient Neopuntia® see glossary has been used since 2000 in more than 150 finished products).

Several clinical studies and trials had since been conducted to demonstrate the safety and effectiveness of using Proactol (Neopuntia®).

Here is a list of significant clinical studies and trials completed on Proactol (Neopuntia®).

• The effect of NeOpuntia® on blood lipid parameters--risk factors for the metabolic syndrome (syndrome X). Published in journal Advances in Therapy. 2007 Sep-Oct, Volume 24(5), Pages 1115-1125.
• A 6-week randomised controlled trial involving 68 women. Our results indicate an advantage of using NeOpuntia® in dietary supplements and functional foods because of improvement of blood lipid parameters associated with cardiovascular risks.
• CERN Pilot clinical study--2003 Not published in any journal.
• A 1-week clinical study involving 10 healthy volunteers. The results of this double blind study, controlled by placebo, randomized and crossed on 2 groups suggest that the daily consumption of NeOpuntia® for one week favours the excretion of fat.

How much Weight can You Expect to Lose using the Diet Pill? [Top]

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You can expect to lose about 10% more weight for taking either Alli or Proactol diet pills than not taking them. On average, you can lose about 1 to 3 pound (0.5kg to 1.3kg) per week for taking the diet pills and following the recommended lifestyle.

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Fat Blocking/binding Capability

Alli and Proactol diet pills can remove up to 25% and 28% of dietary fats respectively. This percentage translates to about reducing 19 grams of dietary fats per day, or an equivalent of 171 Calorie per day or 10% of your Calorie intake per day.

Our computation is based upon a typical American (18 years and older) with a daily Calorie intake of 2047 and total dietary fats intake of 76.4 gram per day.

References

• Fat blocking/binding capability of Alli is obtained from Alli official site - FAQ.
• Fat blocking/binding capability of Proactol is obtained from Proactol official site - How Proactol Works.
• Statistics of a typical American's dietary profile is obtained from United States Department of Agriculture, Economic Research Service.

Weight Loss Results

Both Alli and Proactol come with their own step-by-step integrated action plans which work hand-in-hand with the weight loss pills to help you achieve your weight loss target even faster and easier. If you follow the action plan and take the weight loss pill together, you can expect to lose about 1 to 3 pound a week.

References

• Weight Loss Results from taking Alli is obtained from Alli official site - Real User Stories.
• Weight Loss Results from taking Proactol is obtained from Proactol official site - User's Testimonial.

How each Diet Pill Helps You in Losing Weight? [Top]

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Both Alli and Proactol help you by reducing up to 28% of dietary fats that will be otherwise absorbed into your body.

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We will explain the mechanism of Alli and Proactol in losing weight. Both weight loss pills serve to reduce the amount of dietary fats absorbed into your body from food intake but they do it in slightly different ways.

Alli Diet Pill

Alli focuses on disabling enzymes in your digestive system. Before any dietary fats can be absorbed into your body, they need to be broken down into "smaller pieces" and this is done by the actions of enzymes. Since Alli inactivates some of these enzymes, less dietary fats are being absorbed into your body.

Proactol Diet Pill

Proactol surrounds the dietary fats making them into "bigger pieces" and at the same time this prevents the enzymes from coming into contact with the dietary fats. Hence less dietary fats are absorbed into your body.

Known Side-Effects of each Diet Pill [Top]

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Taking Alli diet pill can lead to some uncomfortable treatment effects such as loose stools and can affect normal absorption of fat-soluble vitamins; Proactol has no known side effect.

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Effectiveness of diet pill is one thing but you must also consider whether there will be any side-effects for taking the particular diet pill.

Proactol Diet Pill

No known reported side-effects at current time.

Alli Diet Pill

Taking Alli may lead you to some uncomfortable side-effects also known as treatment effects. You may experience more frequent stools that may be hard to control, gas with oily spotting and loose stools.

Taking Alli does interfer with the absorption of essential fats-soluble vitamins and minerals. It is therefore recommended to take a multivitamin supplement when taking Alli.

The side-effects information are obtained from the manufacturer's website.

Diet Pill Ingredients [Top]

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Alli is a synthesized chemical and is non-vegetarian and non-Kosher; Proactol is 100% natural and organic and is certified Kosher and suitable for vegetarian.

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We will share with you what each diet pill contains and whether it is suitable for vegetarians or it is Kosher.

Proactol Diet Pill

Active Ingredient: 535mg Opuntia ficus-indica fiber complex (granulated)

Opuntia ficus-indica fiber complex (NeOpuntia®) see glossary is a natural occurring substance extracted from a cactus plant.

Non-active Composition:

• Microcrystalline cellulose
• Calcium hydrogen phosphate dihydrate
• Silica
• Povidone
• Magnesium stearate

Proactol is a herbal supplement and therefore it is suitable for vegetarian.

Alli Diet Pill

Active Ingredient: 60mg of Orlistat

Orlistat is a synthesized chemical called Tetrahydrolipstatin see glossary.

Non-active Composition:

• FD&C Blue No. 2
• Edible ink
• Gelatin
• Iron oxide
• Microcrystalline cellulose
• Povidone
• Sodium lauryl sulfate (sulfur)
• Sodium starch glycolate
• Talc
• Titanium dioxide

The gelatin of the capsule of Alli pill is made from components of animal origin. It may be of bovine or pork origin. Therefore Alli is not Kosher and non-vegetarian.

Cost of each Diet Pill [Top]

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Alli costs US$2.33/day; Proactol costs US$3.00/day.

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You won't want to burn your pocket to lose weight. Determine whether Alli or Proactol is a more affordable choice.

Alli Diet Pill

A) Dosage for Losing Weight: 1 capsule 3 times a day.

Items	Cost
60 pills pack (smallest available size)	US$44.99
	US$2.25 / day
Centrum© multivitamin (130 tablets)	US$10.99
	US$0.08 / day
Total Cost per day	US$2.33 / day

Proactol Diet Pill

A) Dosage for Losing Weight: 2 capsules 3 times a day.

Items	Cost
120 pills pack (smallest available size)	US$89.95
	US$4.50 / day
Total Cost per day	US$4.50 / day

B) Dosage for Maintaining Weight: 2 capsules 2 times a day.

Items	Cost
120 pills pack (smallest available size)	US$89.95
	US$3.00 / day
Total Cost per day	US$3.00 / day

Are there any Guarantee? [Top]

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Proactol comes with a 180-day money back guarantee; Alli does not offer any money back guarantee.

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A money back guarantee speaks for itself. You are protected against any monetary lose for trying the diet pill if it comes with a money back guarantee. A more important aspect is that you can be more assured of the effectiveness of the diet pill if it comes with a money back guarantee. No business will be foolish enough to offer a money back guarantee if the product is not going to work.

Proactol Diet Pill

Proactol comes with a 180-day money back guarantee which is one of the longest that you can find in the diet pill industry. The money back guarantee provide full assurance that if you don't lose weight for trying the full system for 120 days, then you will get a full refund.

Experience Proactol now with a complete peace of mind.

Alli Diet Pill

The manufacturer does not directly offer any money back guarantee. However Alli Diet Pill is available through a number of third-party sale channels and these third-parties can offer thier own money back guarantee scheme which can be up to 60-day.